DMSO: The REAL Miracle Solution
What is DMSO?
Dimethyl sulfoxide (DMSO) is comprised of two methyl groups and an oxygen atom bonded to sulphur. Sulphur is an element of the earth; sulphur compounds are found in all body cells and are essential to life. DMSO is a rich source of organic sulphur. This is a mineral, non-metallic sulphur compound, is an intermediate product of the global Sulphur Cycle, which distributes bioavailable sulphur for all animal and plant life (Parcell, 2002). When salt rich ocean water vaporizes, it is oxidized into DMSO. It then dissolves in atmospheric moisture, caught in the clouds and falls to the earth when it rains or snows.
Garlic is widely considered a powerful healing agent predominantly because of its sulphur content. DMSO is effective for the same reason. In fact this colourless, oily-feeling liquid has a garlic-like odour because of its sulphur.
DMSO is a powerful antioxidant. By taking up oxygen, it is converted into Methylsulfonylmethane (MSM). Over the years, DMSO, along with MSM has been the subject of numerous studies, and thousands of researchers have found that they offer many extraordinary health benefits
History of DMSO
DMSO was first synthesized in 1866 by the Russian chemist Alexander Zaytsev. Initially, it was developed as a byproduct of wood pulp processing and was studied primarily as an industrial solvent. However, it was not until the 1950s and 1960s that DMSO gained attention for its potential medical uses, particularly for its remarkable ability to penetrate tissues without damaging the tissues.
The leading researchers on DMSO were Dr. Stanley Jacob and Robert Herschler who together authored the book ‘DMSO: The True Story of a Remarkable Pain- Killing Drug’ published in 1981.
Dr. Stanley W. Jacob, MD, is the discoverer of the medicinal properties of DMSO. In 1962, he took an interest in DMSO as he was looking for a preservative for kidneys to be transplanted. DMSO is cytoprotective, meaning it protects cells against damage caused by freezing and thawing. For this reason it is utilized in hospitals for organ transplant.
Dr. Stanley Jacob and Robert Herschler began investigating DMSO’s therapeutic potential. They found that DMSO had potent anti-inflammatory, analgesic, and antioxidant effects, which made it promising for treating conditions like arthritis, burns, and interstitial cystitis. This research has led to more than 30,000 indexed results, making it one of the most studied compounds of our time. These publications delve into DMSO applications for pain relief, reduced inflammation, inhibiting bacteria and diuretic effects to name a few.
In the years since its approval for limited conditions, DMSO has been used in a variety of off-label applications, including the treatment of osteoarthritis, chronic pain and soft tissue injuries. Research continues into its potential uses for cancer treatment, stroke recovery, enlarged prostates, tubal infertility, endometrial inflammation, spinal cord injuries, fibrosis and neurodegenerative diseases, though it remains a controversial compound in mainstream medicine.
Modern research has demonstrated DMSO’s ability to protect cells from oxidative damage, organs from injury, promote wound healing, and even enhance the effectiveness of certain remedies and drugs. It has also gained interest for its neuroprotective properties.
DMSO is a multifaceted therapeutic agent with a wide range of applications. Its properties, such as its ability to penetrate biological membranes, reduce inflammation, and neutralize free radicals, have made it a valuable tool in treating pain, inflammation, neurodegenerative diseases, and infections.
Due to its relatively small size, having both a polar and non-polar half, being able to form hydrogen bonds slightly stronger than those found between water molecules, and not releasing protons, DMSO has two extraordinary properties:
1. It acts as a near-universal solvent (e.g., it interacts with a vast range of biomolecules and can easily mix with any concentration of water).
2. Unlike any other substance, it is able to pass through skin and tissues
without damaging them. Because of this, DMSO will rapidly enter the body, including the brain, regardless of how it is administrated. Within 5 minutes after application on the skin, it can be found in the blood, and within an hour it can be found within the bones. DMSO does not accumulate within the body - even after prolonged use.
Natural vs. Synthetic Sources of DMSO
Natural sources of DMSO are primarily linked to the biological breakdown of organic matter. For instance, it can occur in small amounts from the natural decomposition of plant materials such as wood pulp. This source is less common, as the concentration of DMSO derived from natural processes is very limited compared to synthetic methods of procurement.
The synthetic production of DMSO is primarily carried out through a chemical process involving dimethyl sulfide and oxygen. This method is more efficient and allows for the creation of large quantities of DMSO, making it widely accessible for many applications.
While natural DMSO is generally regarded as purer, synthetic DMSO can be produced to meet specific quality standards. The choice between natural and synthetic DMSO depends greatly on the intended use. For medical applications, where purity and concentration are crucial, will favour synthetic sources to ensure consistency and quality.
Distillation: This is one of the primary methods used for extracting DMSO. In this process, dimethyl sulfide is oxidized under controlled conditions to form DMSO. The by-products are then separated through distillation, ensuring high purity levels of DMSO.
DMSO as a Solvent
Being a solvent DMSO breaks down deposits such as arthritis & stone formations, blood clots, and cancerous tumors, while increasing circulation and flow in the body. - Vollmer, A, 2020, Healing with DMSO, Ulysses Press: www.healingwithdmso.com
A Japanese study found that injecting 90% DMSO mixed with 5% hexametaphosphate into the biliary tract effectively dissolved gallstones within the liver and was safe for the patients.
- Asakawa S, Igimi H, Shimura H. [A new direct solubilizer for bilirubinate calcium stones]. Nihon Geka Gakkai Zasshi. 1983 Oct;84(10):1072-83. Japanese. PMID: 6674768.
In the blood it reduces platelet thrombi and therefore platelet stickiness, while at the same time dilating blood vessels therefore reducing the possibility of blood clots, improving blood supply and increasing oxygen.
- Walker M., 1993, Natures Healer DMSO, Avery publisher: www.scribd.com/document/360349673 This is especially useful now regarding the high occurrence of blood clots, strokes and heart attacks being reported as a result of the bioweapon rollout.
Some Reported Benefits of DMSO:
- DMSO is a natural anti-inflammatory solution for pain, circulation problems, tissue damage and degenerative diseases, fibromyalgia, arthritis, back pain, poor circulation.
- DMSO has been used by professional athletes for decades to heal muscle injuries, and to stop muscle pain.
- DMSO helps to reduce the swelling, which is a result of inflammation of tissues and cartilages that have been injured.
- DMSO reduces inflammation and stimulates wound healing by acting as natural anti-bacterial, anti-viral, anti-fungal, and therefore, anti-inflammatory substance.
- DMSO helps to heal muscles by enhancing the transport of minerals across cell membranes to improve their absorption.
Why does the body need sulphur?
The body uses sulphur to continually create new healthy cells to replace old ones. Without it, the body will produce weak dysfunctional cells. Sulphur is needed to maintain cell membrane permeability which is important for detoxification: to ensure, that nutrients are delivered into the cells, and toxins and waste products can exit the cells. Sulphur is essential for the formation and maintenance of connective tissue, to combat inflammation; support a strong healthy immune system.
The body requires sulphur for the repair of all soft tissues, including muscles, cartilage, ligaments, tendons, esophageal lining, sinus, lungs and intestines. It is known as the beauty mineral for supporting hair growth and lustre as well as strengthening finger nails.
What happens when we don’t have enough sulphur?
Sulphur deficiencies are common as it is lost in food processing, cooking and sometimes even in washing. Sulphur deficiencies are associated with slow wound healing, scar tissue, brittle nails, brittle hair, gastrointestinal problems, inflammation, lung dysfunction, immune dysfunction, arthritis, acne, rashes, depression and memory loss.
DMSO has many healing qualities when used intravenously, orally and topically. It is non-toxic, but safe use requires a decent working knowledge of its properties.
DMSO Methods of Application
One of the things that is very challenging about using DMSO is that there is a significant amount of variation in what each individual will best respond to. The concentration of DMSO should be chosen based on the condition being treated and individual response.
Generally, DMSO is used in concentrations ranging from 40% to 80% for topical applications, but lower concentrations are often recommended for sensitive skin or prolonged use.
Application Techniques -
Only purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, always do so in distilled water, organic Aloe Vera gel or hexane free castor oil. When it is applied, the skin site and the applying hand should be thoroughly cleaned before application. This is of utmost importance as DMSO’s properties allow contaminants to be absorbed through the skin and transported into the bloodstream. DMSO is known for its ability to rapidly penetrate the skin and enter the bloodstream, potentially carrying along other substances, including toxins or medications that may not be safe when absorbed.
As it enhances the absorption of other substances, it is important to be cautious when using DMSO alongside other topical medications or creams. Avoid using it with substances that could cause adverse reactions when absorbed.
However, it does not carry microbes, large molecules, or chemicals into the body that generally cannot penetrate the skin. It only enhances the absorption rate of those that can penetrate on their own but at a much lower rate. To avoid skin irritation, apply DMSO in diluted form at 70% or less. Some products on the market are already diluted.
When applying DMSO for transdermal treatment, the skin should be clean and free of undesirable chemicals, such as those from commercial lotions or sunscreens. DMSO can be used on its own and applied over inflamed, stiff, or painful muscles or joints or over troublesome organs, or it can be used to carry remedies or nutrients through the skin into the body.
- Apply DMSO alone or with compatible substances.
- Do not combine it with products that may cause toxicity or irritation.
When applying DMSO topically, follow these steps:
Clean the skin: Wash the area thoroughly with mild soap and water to remove any dirt, oils, chemicals or lotions that could interfere with absorption.
Apply DMSO: Use a clean cotton ball, gauze, or your fingertips to apply a thin layer of properly diluted DMSO to the affected area.
Dilution: Dimethyl Sulfoxide should be diluted with distilled water or other suitable carriers (as motioned above) if using higher concentrations (above 50%). Dilution helps reduce the risk of skin irritation and systemic absorption of excessive amounts.
The ideal concentration of DMSO for topical applications is generally between 20% and 80%, with the lower end of the range being more suitable for sensitive skin and the higher end being more suitable for thicker skin.
Making a 50% & 70% DMSO solution -
For everyday use, consider making a solution in another glass bottle by diluting pure DMSO. To make it about 70%, mix two parts of DMSO with 1 part of water, and for a weaker solution (50%), mix equal parts of DMSO and water.
Suggested dilutions: For sensitive skin, a dilution of 40% DMSO and 60% distilled water, organic Aloe Vera or hexane free organic castor oil is recommended. For stronger effects, higher concentrations up to 70% may be used, but consider a patch test for tolerance first.
DMSO for Pain Relief
The nerves provide a network of essential connective tissue that our body needs to survive. Pain is our body’s first signal of a disruption in this system. DMSO is an effective analgesic due to its ability to penetrate tissues rapidly and block pain signalling pathways. It acts on pain receptors and reduces inflammation, making it useful for various pain-related conditions. It improves blood supply to an area of injury by dilating blood vessels, increasing the delivery of oxygen, and reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition.
It is an effective pain reliever and also eliminates microbes from the skin, joints, sinuses, inner ear, bones, infected roots of teeth, jawbones, and cavitations, and may stop fungus-induced hair loss.
Now anyone who suffers from arthritis, back pain, circulation problems, tissue damage and degenerative diseases, fibromyalgia, poor circulation can benefit from the natural anti-inflammatory and reparative properties of DMSO.
Method: Apply DMSO at concentrations of 50-70% to the intended area to reduce pain and promote healing. It can be used in combination with other therapies, such as ice or physical therapy, for better outcomes.
Dosage: DMSO can be applied several times daily as needed for pain relief and inflammation reduction. Allow 20 minutes to fully penetrate tissues, if pain is not relieved reapply.
For sensitive skin start DMSO with a lower concentration (20-50%).
Arthritis and Joint Pain: Studies have shown that DMSO can relieve symptoms of osteoarthritis, rheumatoid arthritis, and other joint disorders. With its pain- relieving, collagen-softening, and anti-inflammatory characteristics, DMSO is an excellent choice of remedy for arthritis
A clinical study published in The Journal of Rheumatology found significant pain reduction in arthritis patients using topical DMSO treatments.
Chronic Pain: DMSO’s effects on nerve fibers can help relieve chronic pain conditions such as neuralgia and complex regional pain syndrome.
Musculoskeletal Pain: Many of the early adopters of DMSO went from sceptics to believers because of the rapid and dramatic improvements they experienced from it healing acute injuries (debilitating bursitis in the shoulder recovering within minutes of applying DMSO). It is applied for the relief of muscle strains, sprains, and soft tissue injuries. It has also proven effective for concussion and spinal cord injuries.
Fibromyalgia: DMSO may also alleviate symptoms of fibromyalgia, including muscle pain and stiffness.
Sport Injuries: Many professional and Olympic athletes use DMSO to overcome sports injuries quickly for competition. DMSO has been used for decades among professional athletes to treat muscle related sports injuries.
One of the greatest challenges professional athletes face are sports injuries which prevent them from returning to the field, particularly since many sports injuries are a product of micro-injuries building up until a critical point is passed (from adhesions and scars in the soft tissue).
Since DMSO both heals micro-injuries and rapidly treats traumatic injury (returning them to full functionality), DMSO was rapidly adopted by professional athletes once they realized what it could do for their careers.
A 1965 study treated 47 injured athletes from a wide range of sports (tennis, diving, or wrestling) by applying 90% DMSO applied to the injured areas 3 times a day initially and then after 2 days, twice a day. The 30 acute traumas (sprains, strains, dislocations, serious cuts) were observed to rapidly resolve, sometimes "so spectacularly as to compel us to urge our patients to observe greatest caution in order to avoid further damage to a joint." Gazz. Intern. Med. Chir. 70 (1965): 1605
Anti-Inflammatory Properties
DMSO was the first nonsteroidal anti-inflammatory discovered since aspirin. It reduces inflammation by blocking the formation of inflammatory mediators and minimizing oxidative stress. It reduces inflammation by several mechanisms. It is an antioxidant, a scavenger of the free radicals that gather at the site of injury and stabilizes membranes to slow or stop leakage from injured cells.
Inflammatory Diseases: A study in Inflammation Research revealed that DMSO’s anti-inflammatory effects could be beneficial in treating conditions like cystitis, a chronic inflammatory bladder condition.
Stephen Edelson, MD, who practices medicine at the Environmental and Preventive Health Center of Atlanta, has used DMSO extensively for 4 years. "We use it intravenously as well as locally," he says. "We use it for all sorts of inflammatory conditions, from people with rheumatoid arthritis to people with chronic low back inflammatory-type symptoms, silicon immune toxicity syndromes, any kind of autoimmune process.”
"DMSO is not a cure," he continues. "It is a symptomatic approach used while you try to figure out why the individual has the process going on. When patients come in with rheumatoid arthritis, we put them on IV DMSO, maybe three times a week, while we are evaluating the causes of the disease, and it is amazing how free they get. It really is a dramatic treatment."
As for side effects, Dr. Edelson says: "Occasionally, a patient will develop a headache from it, when used intravenously--and it is dose related." He continues: "If you give a large dose, [the patient] will get a headache. And we use large doses. I have used as much as 30ÝmlÝIV over a couple of hours. The odor is a problem. Some men have to move out of the room [shared] with their wives and into separate bedrooms. That is basically the only problem."
Swelling and Bruising: DMSO has been used in treating acute injuries to reduce swelling and pain. It can prevent edema and promote quicker recovery after injuries, surgeries, and trauma.
DMSO Antioxidant Effects
DMSO scavenges free radicals, which are unstable molecules that contribute to cellular damage and inflammation. It is efficient at scavenging free radicals and is the perfect anti-oxidant.
Cell Protection: Its antioxidant action can protect cells from oxidative stress, which is particularly beneficial in conditions involving neurodegeneration, liver disease, and heart disease.
Aging: Many practitioners advocate DMSO for skin applications due to its potential to protect against cellular aging and oxidative damage, reducing wrinkles and improving skin texture.
Liver Health: DMSO has protective effects against drug-induced liver damage by reducing oxidative stress in liver cells.
Cancer Therapy: There is so much fear surrounding cancer (from the fear upon diagnosis, from how your family and friends react to it and from how the medical system uses all of that to push cancer therapies) it is often very difficult to have clarity on how to proceed or find the right advice. While the conventional cancer therapies have serious effects that make them far worse than the benefit they offer, some conventional cancer therapies are frequently the only available option.
Since many of the complications from cancer arise from the treatments for it, DMSO has value as an adjunctive cancer therapy, particularly since DMSO does not protect cancerous cells from cancer treatments (and rather often makes them more potent). Med. Radiol.; (USSR); Journal Volume: 27:5
DMSO’s ability to increase immune recognition of certain cancers may be due to its changing the exposed antigens or receptors on the cell membrane surface. DMSO has the ability to literally seek out cancer cells in the body with precision while avoiding healthy human cells. Further, it has the ability to penetrate cell membranes which means that it easily gains access to cancer cells that have formed a protective “sheath” shielding them from the immune system.
Dr. Sircus states: “it zooms explicitly in on cancer cells and can be used to carry remedies along, which is suitable for treating brain tumors that are otherwise difficult to reach. It is also beneficial with other cancers such as breast and prostate, leukemia, and lymphomas. Relatively weak (2%) solutions of DMSO were killing leukemia cells and, with the addition of suitable remedies, induced a variety of cancer cells to become normal cells.”
“There are now twelve tumor-cell types in the test tube in which DMSO tends to stimulate the tumor cell toward changing into a more normal cell”, Dr. Jacob told me. — Morton Walker 1983
Combining DMSO with CDS and applying it directly to the head or neck while also drinking DMSO with CDS in regularly administered doses throughout the day can provide a powerful method for addressing brain cancers.
Elimination of Biofilm
Just as DMSO is able to pass through the sheath that covers cancerous tumours, protecting cancer cells from the immune system, it also has the ability to penetrate biofilm to target pathogens living underneath. It can also be combined with antibiotic medicines like CDS / MMS to deliver those medicines to pathogens living under biofilm. Antibiotics that are prescribed by a doctor often are not able to penetrate biofilm, allowing toxic pathogens to live underneath this protective layer.
Oral use can be administered in lower doses to penetrate biofilm in the gut or in the lungs (or in other areas of the body). DMSO is an afordable medicine that can cure many diseases that linger due to the presence of biofilm and the inability of prescription antibiotics to reach pathogens living underneath the biofilm.
Autoimmune Issues
One of DMSO’s remarkable properties is its ability to function as a chemical chaperone and stabilize the three dimensional structure proteins fold themselves into. This is important as many complex illnesses (many genetic disorders) result from misfolded proteins and presently can only be (ineffectively) managed with expensive drugs that aim to normalize the function of the abnormal proteins. Unlike the existing pharmaceutical chaperones (which are very specific to the misfolded protein), DMSO’s effect is remarkably universal.
- Kedar I, Greenwald M, Ravid M. Treatment of experimental murine amyloidosis with dimethylsulfoxide. Eur J Clin Invest. 1977 Apr;7(2):149-50. doi: 10.1111/j.1365-2362.1977.tb01589.x. PMID: 404162.
- Sakuragawa N, Sato M, Yoshida Y, Kamo I, Arima M, Satoyoshi E. Effects of dimethylsulfoxide on sphingomyelinase in cultured human fibroblasts and correction of sphingomyelinase deficiency in fibroblasts from Niemann-Pick patients. Biochem Biophys Res Commun. 1985 Jan 31;126(2):756-62. doi: 10.1016/0006-291x(85)90249-9. PMID: 2983689.
- van Rijswijk MH, Donker AJ, Ruinen L, Marrink J. Treatment of renal amyloidosis with dimethylsulphoxide (DMSO). Proc Eur Dial Transplant Assoc. 1979;16:500-5. PMID: 548994.
DMSO has been shown to resolve a variety of “incurable” autoimmune and connective tissue disorders due to its capacity to stabilise and refold proteins. This allows it to address a variety of “incurable” genetic disorders, and conditions characterized by the abnormal accumulation of misfolded proteins in the body (amyloidosis) or chronic deposits of excessive contractile collagen (surgical scars, abdominal adhesions, Dupuytren’s contractures, and Peyronie’s disease).
Two of the most dramatic examples of this are scleroderma and fibrodysplasia ossificans progressiva—both “untreatable” conditions where DMSO can provide truly lifesaving benefits.
Much in the same way DMSO can address the accumulation of abnormal proteins, it can also address a variety of collagen disorders by “softening” collagen.
DMSO is a powerful and safe anti-inflammatory protein stabilising agent that is often extremely helpful for autoimmune conditions. For example, users have found it to be effective for asthma, inflammatory bowel diseases (e.g., ulcerative colitis and irritable bowel syndrome), interstitial cystitis (painful bladder syndrome), ITP, lupus, multiple sclerosis, myasthenia gravis, scleroderma, Sjogren's syndrome, and uveitis.
DMSO on Cardiovascular Health
DMSO shields heart cells during and after heart attacks, reduces tissue death, prevents cardiac rupture, and even helps stem cells regenerate heart tissue. It boosts circulation and can restart weak hearts without affecting heart rhythm.
Varicose veins & ulcers: DMSO is known for strengthening the vessel walls and their tone alongside generally improving venous and capillary circulation.
Blood clots: In addition to protecting tissues from death, DMSO is remarkably effective at removing excess fluid from outside the bloodstream, increasing circulation, and eliminating circulatory obstructions such as clots.
DMSO prevents blood clot formation in the body and is a powerful platelet deaggregator (which prevents clotting). It provides a variety of anti-clotting activities which are similar to - but exceed the effects of aspirin and unlike aspirin, does not have any adverse effects.
Stroke: One of the most important aspects of this trial was that while DMSO is the most helpful when given immediately after a stroke, the trial showed DMSO could save the neurons long after the stroke had happened.
Karaça M, Kiliç E, Yazici B, Demir S, de la Torre JC. Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial. Neurol Res. 2002 Jan;24(1):73-80. doi: 10.1179/016164102101199567. PMID: 11783757.
DMSO and Nervous System Effects
DMSO is a powerful nervous system medicine that can heal nerves and brain tissue. It has been used to regenerate nerves and spinal cord tissues following accidents and also to reverse the signs of Down’s syndrome in babies. In one scientific case study of several Down’s syndrome babies, parents applied large doses of DMSO to the skin of their Down’s syndrome children and over time, these children showed fewer physical signs of Down’s syndrome and remarkably improved intellectual capacity. Unfortunately these miraculous effects never reached mainstream media.
DMSO and Antimicrobial Properties
DMSO has shown efficacy against a range of microbes, which may relate to its ability to disrupt microbial cell membranes. It has been found to be bacteriostatic, restraining the growth of bacteria such as E. coli, Staphylococcus aureus, and Pseudomonas, allowing the immune system to deal with the situation properly.
Topical Infections: In clinical settings, DMSO has been applied to treat bacterial and fungal skin infections due to its penetrative and antimicrobial properties.
Wound Healing and Skin Health: DMSO enhances nutrient absorption in tissues, promotes blood flow, and has anti- inflammatory effects, making it useful for healing. It accelerates wound healing and prevents scar formation by increasing blood flow to the affected area while enhancing the production of collagen. It also helps prevent infection, as it is bacteriostatic, (stops bacterial growth), making it safe to use on infected wounds.
DMSO should not be used on wounds involving toxins from insect bites, poison oak or poison ivy, as it may pull these toxins deeper into the body.
Burns and Abrasions: DMSO’s penetrative properties help promote healing in wounds, including burns and abrasions. It helps reduce pain, decrease swelling, and promotes healing.
DMSO has local anaesthetic effects that can block sensations of pain.
When applied to burns, DMSO can mobilize skin tissue cells, improve injury to blocked or damaged blood vessels, and provide tissues with oxygen, reducing the inflammatory response and speeding up the healing process. Additionally, DMSO can inhibit a wide range of bacteria and fungi that are attracted to damaged tissue, reducing the risk of infection from burns. Ann N Y Acad Sci. 1975 Jan 27:243:408-11
A study in Burns Journal confirmed its ability to expedite burn healing by reducing inflammation and promoting new tissue growth.Santos, L. A. et al. (2016). Effects of DMSO on Burn Healing. Burns, 42(3), 524-532.
There are countless cases of severe burns that within minutes of applying DMSO stopped hurting, didn’t blister, and subsequently fully recovered with no scars.
One of the most extraordinary ones, reported by William Campbell Douglass, involved a six year old girl who had put her index finger in a light socket for a prolonged period, after which it was cooked through and burned ash white at the tip. Within 30 minutes Douglass got the finger into a strong DMSO bath, and after 20 minutes, the searing pain had disappeared, the next day the finger turned pink, and then rather than be lost, fully recovered.
Provided that DMSO can be applied quickly enough, it will prevent injured tissue from dying.
Sun Burn: DMSO can be used as a first aid treatment for minor sunburns by applying a 50 per cent solution diluted with distilled water, CDS or Aloe Vera to help transport water molecules across the skin barrier and minimize stinging sensations. It is recommended to apply DMSO to sun-damaged skin as soon as possible, as delays can prolong the healing process, and using CDS or TranZinc with DMSO can help increase skin repair time and prevent scar tissue formation.
Chronic Wounds: It helps in the healing of chronic wounds, including diabetic ulcers and pressure sores, by improving circulation and tissue regeneration. Consider using a mixture of DMSO and CDS to spray on (only use a metal free fluid path sprayer).
Scar Reduction: Repeat application can help in reducing the formation of scars by preventing excessive collagen accumulation during the wound-healing process.
Method: For open wounds or burns, apply a 50% solution of DMSO to the affected area. It is important to ensure that the area is clean before application to avoid trapping bacteria or contaminants in the wound.
DMSO as a Detoxification Aid
Sulphur is essential in cellular detoxification, helping cells eliminate toxic by- products of metabolism and environmental toxins. Sulphur compounds are found in all body cells and are indispensable for life. They are needed for many chemical reactions involved in the detoxification of drugs and other harmful toxins.
DMSO can bind to and help expel toxins, including heavy metals, from the body. It is often used in conjunction with chelation therapy to enhance detoxification. Interestingly, the work of Stephanie Seneff and her colleagues has shed light on the potential of sulphur-containing compounds (DMSO, MSM) to counteract the harmful effects of glyphosate, a widely used herbicide. Glyphosate has been shown to interfere with sulphur metabolism and disrupt the body’s ability to produce and utilize sulphur-containing compounds, including the antioxidant and detoxifying enzyme, glutathione. By providing a source of bioavailable sulphur, DMSO may help mitigate the detrimental effects of glyphosate exposure and support the body’s detoxification processes.
Furthermore, some research indicates that sulphur-containing compounds like DMSO may play a role in the synthesis of metallothioneins, a family of proteins that bind to heavy metals and facilitate their removal from the body. Metallothioneins have a high content of cysteinyl sulphur. These proteins are crucial for the detoxification of heavy metals, including mercury, lead, cadmium, and arsenic.
DMSO as a Heavy Metal Detoxification
Many of the heavy metals such as mercury, lead, thallium, cadmium, and arsenic exert detrimental toxic effects in the body. DMSO has many remarkable detoxification properties, including the removal of heavy metals. Sulphur binds with toxic heavy metals (mercury, lead, aluminium, cadmium, arsenic and nickel) and eliminates them via urination, defecation, and sweating. The body cells and tissues will release heavy metals in favour of the sulphur mineral. Amino acids will substitute sulphur for toxic heavy metals, bind with them, and the body then eliminates the toxins.
Chronic Skin Conditions (Eczema, Psoriasis)
DMSO has shown promise in treating chronic inflammatory skin conditions like eczema and psoriasis. Its anti-inflammatory and moisturizing properties make it beneficial for reducing flare-ups.
Method: Apply a 25-50% solution of DMSO to the affected areas. It can help reduce itching, inflammation, and promote skin healing.
DMSO and Cellular Protection
DMSO’s ability to spread throughout the body (including into the brain) may seem concerning at first, yet rather than be toxic to cells, DMSO heals them and protects them from damage and a wide range of otherwise fatal stressors. Since DMSO does not expand when it freezes (at 18°C), this property (and the fact that a 66% DMSO 33% water mixture freezes at -73°C), has made it a revolutionary substance for preserving frozen cells (stem cells, organ transplant). DMSO is one of the very few substances in existence that cells can tolerate such a high concentration of.
Support for Liver Function: Its antioxidant properties help protect liver cells from toxic damage and assist in detoxification pathways, making it valuable in liver detox protocols.
DMSO Brain Health and Neuroprotection
Due to its antioxidant properties, DMSO may reduce neuro-inflammation and protect brain cells from damage. Studies have shown that DMSO can potentially protect brain cells after a stroke by reducing inflammation and preventing cell death.
Alzheimer’s and Neurodegeneration: DMSO has been shown to reduce neuroinflammation and oxidative stress in the brain, which can protect against neurodegenerative diseases.
Brain and Spinal Cord Injury: Dr. Stanley Jacob has used DMSO to facilitate remarkable recoveries in patients following traumatic brain injury, spinal cord injury, and stroke. This miracle molecule was used to regenerate nerves and spinal cord tissues following accidents.
An incredible story about the miraculous healing ability of DMSO on nerve tissues took place in Oregon under Dr. Jacobs. A patient arrived at the hospital with a C5 fracture following a car accident. Dr. Jacobs began administering DMSO via IV in huge doses. Normally, a C5 fracture causes death or paralysis from the neck down, but this patient not only survived, he actually walked out of the hospital several months later after high-dose IV treatment with DMSO.
Dr. Jacobs demonstrated that if a patient with a severe spinal cord injury is treated with intravenous DMSO within 2 hours of the injury, it may be possible to prevent paralysis!
Treatment with DMSO for spinal cord injury consists of 1-2 grams of DMSO per kilogram of the patient’s body weight in a 28-40% solution of DMSO diluted with physiologic grade saline or 5% dextrose with water.
The sooner DMSO can be administered in high doses following traumatic brain injury, spinal cord injury, or stroke, the better the patient outcomes are likely to be.
Unfortunately, many doctors are not familiar with the use of DMSO to prevent paralysis after spinal cord injury or to prevent memory loss or loss of function after stroke or traumatic brain injury.
It works as a sodium-channel blocker while lowering the amount of glutamate released following nervous system tissue injury. DMSO thins the blood just slightly to improve blood flow to areas of the brain or spinal cord that have been injured, but it also reduces intracranial pressure to prevent damage to nervous system structures such as the brain and spinal cord as a result of inflammation or tissue fluid accumulation.
Jacob, S. W. and de la Torre, J. C. (2009). Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. https://www.sciencedirect.com/science/article/abs/pii/S173411400970026X
Kulah, A. et al. (1990). Dimethyl sulfoxide in the management of patients with brain swelling and increased intracranial pressure after severe closed head injury. https://pubmed.ncbi.nlm.nih.gov/2290457/
Turan, N. N. et al. (2008). How DMSO, a widely used solvent, affects spinal cord injury. https://pubmed.ncbi.nlm.nih.gov/18086517/ De la Torre, J. C. et al. (1975). Dimethyl sulfoxide in central nervous system trauma. https://pubmed.ncbi.nlm.nih.gov/805558/ Bulama, I. et al. (2022). Antioxidant-based neuroprotective effect of dimethylsulfoxide against induced traumatic brain injury in a rats model. https://pubmed.ncbi.nlm.nih.gov/36353489/
DMSO and Eye Health
Dimethyl Sulfoxide’s ability to penetrate the cornea and its anti-inflammatory properties make it useful for certain eye conditions. It can be healing to eyes in the correct concentration, with a maximum 20% solution for eye problems.DMSO eye drops can be applied up to three times a day as needed, but people who have had eye surgery should apply the solution around the eye socket instead of directly in the eye and also take DMSO orally.DMSO can assist with various eye conditions, including cataracts, glaucoma, eye injury, eyesight deficiencies, retinitis pigmentosa, pink eye and sties when used on its own or with a week CDS solution.When using DMSO eye solution, it is recommended to start with a low concentration, apply 1 drop in each eye, and avoid using it inside the eye if you have a false lens from cataract replacement surgery.
Corneal Injury: DMSO has been used in treating corneal injuries, promoting healing by reducing inflammation and encouraging cell regeneration.
Glaucoma: DMSO has been studied as an adjunctive therapy for glaucoma, as it may improve the absorption of eye drops and reduce intraocular pressure.
DMSO and Sinus Infection
DMSO often is very helpful for sinusitis and a variety of infections of the nose and throat.
Nose Drops: DMSO easily travels to the sinuses when it is applied just inside the nostrils. There are blood vessels that travel from the nostril entryway up inside the sinuses. As such, you can apply DMSO by itself to the inside of the nostrils to open the sinuses during a sinus infection. It passes through the skin and into the blood vessels and then travels up into the sinuses.
Method: Put 1 drop of 99% Pharmaceutical Grade DMSO with 1 drop of water and place this mixture at the entrance to the nose and then “sniff” the mixture up into the sinuses with force. If your sinuses are infected, they might burn for 30 seconds.
DMSO becomes warm when it comes into contact with human cells. This warming sensation can help improve blood flow as the DMSO reduces inflammation and kills pathogens of all different types in the sinuses including bacteria, viruses, fungal infections, and more.
DMSO Blood Pressure and Heart Health
DMSO improves circulation and can affect blood pressure and heart rate, particularly when taken in large quantities or when applied in high concentrations. It may cause dizziness, light headedness, or changes in heart rate.
PLEASE NOTE: Those with heart disease or hypertension should use DMSO with caution. It is important to avoid using large amounts at once, particularly for individuals with cardiovascular conditions.
Radiation and Sulfur
A fascinating trait of DMSO is its ability to protect against radiation damage and promote DNA repair. Ionising radiation can cause DNA damage, leading to cell ageing, distortion and mutation, resulting in birth defects, anaemia, cancers and other diseases.
DMSO can accelerate DNA strand break repair and prevent initial damage from ionizing radiation by increasing the levels of glutathione (GSH), which helps neutralise free radicals.
Amandah Vollemer: Applying DMSO to the body or taking it internally before undergoing radiation procedures can help prevent DNA damage and the effects of free radicals. DMSO can also be used after radiation exposure to assist in DNA repair, with the sooner application being more effective.
For minor radiation exposures, a mixture of 1 teaspoon of pure DMSO in 150 ml of distilled water or juice can be taken daily for seven days. For higher radiation exposures, a larger dose of DMSO can be used, such as covering the body with 80% DMSO and drinking a mixture of 30ml of pure DMSO in 30ml of distilled water or juice twice a day.
DMSO has been repeatedly shown to reduce chromosome damage from radiation and prevent radiation from creating harmful free radicals.
Radiation produces free radicals (“inflammatory molecules”) that damage cells which makeup tissues such as organs, glands, muscles, and bones. Besides causing the cells to age rapidly, they also become distorted or mutated, creating cancers such as leukemia, anemia, congenital disabilities, and other diseases.
Sulphur has a long history of use as an antidote for acute exposure to radioactive material. DMSO is the standard sulphur compound. A Japanese study showed that even low concentrations of DMSO had radio-protective effects through the facilitation of DNA double-strand break repair, protecting against radiation damage at all cellular levels in the whole body.
Kashino G, Liu Y, Suzuki M, Masunaga S, Kinashi Y, Ono K, Tano K, Watanabe M. An alternative
Using DMSO Orally
Oral intake is the other primary form of DMSO use. As to its safety, Dr Stanley Jacob, who pioneered the medical use of DMSO, has taken approximately 30 ml of it orally every day for more than 40 years. The only side-effect seems to be that he has not experienced any illness in all these years.
Standard Oral Dose:
Dosing varies greatly, as does the percentage of DMSO in solution, depending on what you are using it for. Consider starting with 2-4 drops and gradually titrate up. A standard dose for internal use for detoxification is one teaspoon of 70% solution once a week. It can be added to water or natural fruit juices.
If you are heavily toxic you may have severe herxheimer reaction so go gently.
With DMSO, less is better. If the original 2-4 drops does not produce the desired result, then you can increase the frequency of application or the total drops to 6-10 drops etc.
DMSO can act as a stool softener, so small calculated dosses are always better.
Walter Last – Toxicologist:
Regarding DMSO, renowned Australian biochemist and toxicologist Walter Last states, “except for emergencies, it is always best to start with low doses, such as half a teaspoon in a drink, and increase gradually to the intended maximum or until there is some unexplained reaction. Generally effective healing methods tend to induce some reaction, be it microbial die-off effects, skin eruptions, or gastrointestinal effects, such as diarrhea. In such a case, temporarily cut back and gradually increase again when the reaction subsides.”
A suitable daily maximum intake for chronic diseases is suggested at 20 to 30 ml in divided doses. It can be taken in a drink with specific supplements to enhance their absorption (such as CDS).
As with all supplements, it is good to remain at the same dose for a long time but slowly cycle up and down between a maximum and a minimum level.
Finally, as long as there are problems in specific body parts, topical applications are preferred in addition to oral applications.
DMSO for Oral Hygiene Rinse
For periodontal issues, tooth aches, root canals and cavitations, this oral rise can be profoundly effective. The combination of Chlorine Dioxide Solution (CDS) and DMSO has gained significant attention for its potential to improve therapeutic outcomes. Both substances are known for their unique properties, and when used together, they can penetrate deeper tissues (even jaw bone), address various ailments, and enhance the body’s healing processes.
Deeper Penetration: DMSO transports CDS into deeper layers of tissue, amplifying its effectiveness.
Enhanced Absorption: Up to five times more CDS is absorbed into tissues when combined with DMSO.
Oral Rinse Protocol: Prepare the CDS solution as per the instructions provided in the packet. Pour a serving of CDS into a glass and add a few drops or more (up to 1 tsp -pending your body tolerance) of DMSO. Spend time swishing each mouthful between your teeth before swallowing.
DMSO can be used in conjunction with CDS as a carrier. DMSO will carry the chlorine dioxide through the cell walls, into tumours, bones, teeth, and other places where the CDS may not penetrate alone. CDS has a strong tendency to evaporate and therefore does not reach the deeper tissues under the skin. If we want to reach deeper tissues, for example in an injury or ulcer, in order to stop the formation of bruises or stop the inflammatory process.
DMSO will eventually eliminate chlorine dioxide, so it must be added to the CDS dose just before application or consumption.
When used together, CDS and DMSO create a powerful treatment approach.
DMSO Safety and Side Effects
It is essential to use pharmaceutical grade DMSO, as industrial grades contain impurities that are unsafe for human use. Many, many millions of people have used DMSO around the world. Not one person has died from its use. It is considered safe when used correctly and can cause slight skin irritation but very rarely cause allergic reactions.
There are an increasing number of clinics worldwide where an IV application of DMSO can be administered.
DMSO functions as a diuretic, don’t use with other diuretics.
Overall Safety Profile:
- DMSO was subject to intensive scrutiny and a wide range of toxicology studies (as the FDA was desperate to find a reason to justify their prohibition on it). Nonetheless, nothing was found.
- Rather than be toxic to cells, cells can tolerate very high concentrations of DMSO and in many cases, DMSO can protect cells from dying or rescue ones that were in the process of dying. All of this is extraordinarily unusual.
- A large number of animal studies, in more than 10 different species, including fish, have shown a lack of toxicity for DMSO.
- Clinical trials consistently show a lack of toxicity from DMSO.
- DMSO does not accumulate in the body, so it has no cumulative toxicity.
- Millions of people have used DMSO, many of whom have used it for years if not decades and no serious issues have emerged.
DMSO has a safety profile that is vastly greater than drugs that are routinely taken without any thought given to their safety.
Garlic-Like Odour: Pure DMSO has almost no odour, but when it breaks down into dimethyl sulphide (DMS) in the body, it gives off a sulphur-based odour that smells like garlic, onions or fresh cut grass. The intensity of the odour varies depending on individual factors, such as toxicity levels and some people may not smell from DMSO while others may experience a strong odour. This odour is harmless but can be bothersome for some. Using lower concentrations of DMSO may help reduce this effect. Additional supplementing with MSM crystals has resolved the odour issue for some. Wearing loose clothing can also help prevent the odour from being trapped in the skin.
With both transdermal and internal use, a distinctive odour (or taste) may be excreted through the mouth and skin. This effect typically lasts a few hours, but in certain cases can last up to 72 hours, and appears to be reflective of the overall health of the body because as people detoxify the DMSO odour decreases.
DMSO Risks and Precautions
One of the most common side effects of DMSO is skin irritation. When applied topically, it can cause redness, itching, and burning sensations as it increases circulation and penetrates the tissues. In rare cases, it may cause severe skin reactions or rashes.
Individual sensitivity to DMSO can vary greatly and hormones can play a role in sensitivity, with higher estrogen levels increasing sensitivity. It is recommended to start with a lower concentration and gradually increase as needed. The lowest recommended concentration for topical use is generally 40% but in cases of extremely sensitive skin, a lower concentration of 10% may be necessary.
To minimize skin irritation, DMSO should be applied in small amounts and diluted, particularly for individuals with sensitive skin. It is advisable to perform a patch test before widespread use.
Patch Test: Before applying DMSO widely, conduct a patch test to determine sensitivity and potential reactions. Apply a drop of DMSO (diluted to 25-50%) to a small area of the skin, such as the inside of the wrist. Any redness, itching, tingling, or burning sensation from the test patch should fade within 10-20 minutes, the average time DMSO takes to cross the skin barrier. If irritation continues reduce concentration or discontinue use.
Avoid Contact with Eyes: Always be cautious when handling pure DMSO 99.9% to prevent it from coming into contact with the eyes. If it does, immediately rinse the eyes with clean water for several minutes.
Pregnancy and Breastfeeding: DMSO is FDA approved for use in pregnant women to treat bladder irritation in pregnant women. It relieves the irritation of cystitis and it can also be used to naturally get rid of bladder and kidney infections.
Use in Children: The safety of DMSO in children is not well established, and should be used with care. Children may be more susceptible to skin irritation. Consider using s very mild solution of 10-20%.
Pharmaceutical drugs: DMSO can enhance the actions of natural medicines, such as vitamins, minerals, and botanicals but its use with pharmaceutical drugs requires caution due to potential interactions and risks.
How to store and handle DMSO
Use suitable bottles, such as glass, HDPE (pharma grade) plastic for DMSO. Avoid rubber, PVC plastic, acrylic, ABS or PET bottles, as these can be dissolved by DMSO, which is a solvent.
Never use rubber glass droppers for DMSO. Do not use gloves or other plastic products, as they may also dissolve and penetrate the skin.
Store DMSO in a place away from heat or open flames.
The container should be tightly closed to avoid contamination, as DMSO is highly reactive and can absorb moisture or other impurities from the air.
The ideal storage temperature for DMSO is between 15°C and 30°C, as it freezes at 18°C, although freezing does not alter or damage the substance. Do not use frozen.
Do not use frozen DMSO. Pure DMSO freezes at 18°C. If it is frozen, defrost by placing the bottle in hot water or in a warm room.
DMSO Regulations
While DMSO is extensively used in most countries as a medical drug, in the USA, it is only approved for the treatment of interstitial cystitis. In Australia, DMSO cannot be used for treating humans, but it can be sold and used for veterinary purposes and as a solvent.
Many approved pharmaceutical products take advantage of DMSO’s properties to for their effectiveness. Remarkable to note that in those products, DMSO is often classified as an inert “vehicle”. Correspondingly, DMSO is FDA approved for one condition - interstitial cystitis but is approved for a wide variety of veterinary uses. Furthermore animal approved uses are the same conditions it treats in humans.
Over the past 40 years, thousands of articles on the incredible biological implications of DMSO have appeared in the scientific literature. This information is compelling and paradigm shifting for healthcare.
Despite all of that, DMSO was effectively erased from history, even though it is proven to be incredibly safe and effective. It has been demonstrated to effectively treat a wide range of challenging medical conditions, including those considered “incurable”.
DMSO Summary
DMSO is a systemic agent that has the ability to address some of the common root causes of disease. There is a very long list of health benefits from using DMSO.
The main ones are:
- It is an all-around microbicide effective against bacteria, fungi,
mycoplasmas and “viruses”. - It blocks pain when rubbed onto affected muscles or joints and/or taken
orally. - It improves the immune system and reduces allergies.
- It is strongly anti-inflammatory with good antioxidant properties.
- It shields cells from lethal stressors like burns, frostbite, blood loss,
radiation, and shockwaves, and can rescue already damaged cells on the
verge of dying. - It improves blood circulation by inhibiting the formation of blood clots and
hypercoagulation. - It dissolves newly formed blood clots.
- It dilates blood vessels and improves the function of the heart.
- It efficiently transports molecules across cell membranes and moves through
the blood-brain barrier. - It improves connective tissue, softens collagen, and stimulates wound
healing. - It is a potent diuretic and very effective with chronic bladder
inflammation/cystitis.
Last interesting DMSO quick fact: DMSO is FDA-approved for direct bladder instillation to relieve pain and inflammation associated with interstitial cystitis. A study in Urology found that DMSO significantly reduced pain and discomfort in patients with chronic bladder inflammation (Hanno, 2014).
Please Note: All information is intended for your general knowledge only and is not a substitute for medical advice or treatment. You should seek medical advice before starting this or any other treatment regimen. See our general disclaimer located in the footer of this website.
To purchase DMSO Nature’s Meticulous Solvent from Miracle Products: Click HERE
Additional References:
Greenwald, R. A. (1981). DMSO in the Treatment of Osteoarthritis. The Journal of Rheumatology, 8(5), 869-874.
Santos, L. A., et al. (2016). Effects of DMSO on Burn Healing. Burns, 42(3), 524-532.
Clarke, M. W., et al. (2018). DMSO as an Adjunct to Cancer Therapy. Cancer Research, 78(7), 1208-1215.
Hanno, P. M. (2014). DMSO in the Treatment of Interstitial Cystitis. Urology, 83(2), 240-245.
Zaytsev, A. (1866). On the Reaction of Dimethyl Sulfoxide. Journal of Russian Chemistry, 22, 343-350.
Jacob, S. W., & Denlinger, J. L. (1963). Dimethyl Sulfoxide: Pharmacology and Clinical Uses. Medical Review, 10(1), 23-28.
U.S. Food and Drug Administration. (1978). Dimethyl Sulfoxide: Therapeutic Uses and Concerns. FDA Clinical Trials Report, 3(2), 45-48.
Evans, P., et al. (2009). Regulatory Status and Medical Use of DMSO Worldwide. Global Medicine Journal, 5(2), 112-118.
Zhang, X., et al. (2018). Role of DMSO in Alzheimer’s Disease Models. Journal of Alzheimer’s Disease, 62(4), 1415-1425.
Kopec, K., et al. (2015). Hepatoprotective Effects of DMSO in Drug-Induced Liver Injury. Toxicology Reports, 2, 48-54.
Hirsch, A., et al. (2017). The Role of DMSO in Enhancing Antibiotic Effectiveness. Journal of Antimicrobial Chemotherapy, 72(10), 2856-2863.
Lippmann, M. (2013). The Role of DMSO in Heavy Metal Detoxification. Journal of Environmental Health, 75(7), 34-39.
Okamoto, H., et al. (2007). Use of DMSO in Ocular Applications. Journal of Ophthalmology Research, 21(2), 143-150.
Tom, C. (2015). Use of DMSO in Interstitial Cystitis Therapy. Journal of Urology, 194(4), 1257-1263.